How to start an investigator-initiated trial as a cardiology fellow or young clinical investigator?
How to start an investigator-initiated trial as a cardiology fellow or young clinical investigator?
A stepwise strategy of planning and conducting an Investigator-initiated trial– from Liu and Dai, JACC66: 3, 2015, 324-327 https://doi.org/10.1016/j.jacc.2015.06.002
The 10 steps ( please refer to original article for details)
- Ask a clinically important and novel question.
- Find a mentor.
- Find collaborators, locally or through networking.
- Getting funded.
- Institutional review board and clinical trial office process—appropriate expectation and planning.
- Putting together a good team is essential.
- Supporting environment and resources—improvisation and improvement.
- Balancing between clinical duty and research—for now, and for the future as a cardiologist.
- Aim for meaningful publications—design, execution, and analysis.
- Timing. it is never too early to start planning for your trial during fellowship or early career.